Exosomes: Tiny Messengers for Cellular Communication

**Exosomes: Tiny Messengers for Cellular Communication**

Exosomes are microscopic vesicles secreted by cells that play a key role in cell-to-cell communication. Think of them as biological delivery systems that carry proteins, growth factors, and genetic material to help neighboring cells repair and regenerate.

In aesthetics, exosomes are used in topical therapies to boost collagen production, reduce inflammation, and improve skin texture and elasticity. They are often combined with microneedling or laser treatments to enhance results. While the FDA has not approved exosomes as stand-alone therapies, they can be legally used as topical solutions in conjunction with FDA-cleared devices like microneedling pens for cosmetic purposes.

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 **PRP: A Natural Boost from Your Own Body**

Platelet-rich plasma (PRP) is derived from a small sample of your blood. The blood is spun in a centrifuge to isolate platelets and plasma, which are rich in growth factors that promote healing and tissue repair.

PRP has gained FDA approval for certain orthopedic and dental applications. In aesthetics, it is used off-label to rejuvenate the skin, improve hair growth, and treat under-eye hollows. PRP can be injected or applied topically following procedures like microneedling or laser resurfacing to accelerate healing and enhance skin renewal.

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**PDGF: The Growth Factor Superstar**

Platelet-derived growth factors (PDGF) are among the bioactive proteins found in PRP. PDGF is a powerful player in tissue repair, stimulating cell growth, collagen production, and blood vessel formation.

In the U.S., PDGF is FDA-approved for treating chronic wounds and ulcers but is also widely used off-label in aesthetic medicine. When applied to the skin via microneedling or mixed into serums, PDGF supports faster recovery and promotes a smoother, more youthful complexion.

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### **Polynucleotides: Repair at the DNA Level**

Polynucleotides are long chains of nucleotides, the building blocks of DNA. These molecules are derived from natural sources like salmon DNA and are prized for their ability to repair damaged skin, hydrate deeply, and combat signs of aging.

Polynucleotide treatments are gaining popularity for their ability to restore skin’s elasticity and firmness. While they are not FDA-approved as injectables in the U.S., they can be used topically in combination with FDA-cleared aesthetic devices like microneedling pens or lasers to boost collagen and cellular repair.

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 **How These Innovations Fit into U.S. Regulations**

Understanding how these therapies are approved and used in aesthetics is crucial. The FDA regulates treatments and devices to ensure safety and efficacy. Exosomes, PRP, PDGF, and polynucleotides are primarily used off-label in aesthetic medicine, meaning they are not FDA-approved specifically for cosmetic purposes but are allowed when performed by licensed professionals using FDA-cleared devices. Always ensure you seek treatments from a reputable, experienced medical provider who prioritizes safety and transparency.

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**Rejuvenate with the Power of Science**

At Blossom Medical, we’re committed to offering the most advanced, science-backed treatments to help you achieve your aesthetic goals. Whether you’re interested in PRP facials, exosome therapy, or treatments with polynucleotides, our expert team will tailor a solution designed for your unique needs.

Ready to explore what regenerative aesthetics can do for you? Contact us today for a consultation and start your journey to glowing, youthful skin.